Dick Cavett on depression [bypass NYT article limit with NYClean]:

I’ve decided that the single worst thing about this illness is its terrible authority. I mean the way it thunders at you, “This is the reality. This is how it is and how it’s going to be. Any memories of fun or wellness are flukes, delusions. And will never come again. Now you have 20/20 vision and see life for the dreadful mess it really is.”

depression dick cavett new york times

Peter D. Kramer: In Defense of Antidepressants

The New York Times [bypass NYT article limit with NYClean]:

In terms of perception, these are hard times for antidepressants. A number of articles have suggested that the drugs are no more effective than placebos.

Last month brought an especially high-profile debunking. In an essay in The New York Review of Books, Marcia Angell, former editor in chief of The New England Journal of Medicine, favorably entertained the premise that “psychoactive drugs are useless.” Earlier, a USA Today piece about a study done by the psychologist Robert DeRubeis had the headline, “Antidepressant lift may be all in your head,” and shortly after, a Newsweek cover piece discussed research by the psychologist Irving Kirsch arguing that the drugs were no more effective than a placebo.

Could this be true? Could drugs that are ingested by one in 10 Americans each year, drugs that have changed the way that mental illness is treated, really be a hoax, a mistake or a concept gone wrong?

peter d. kramer antidepressants psychiatry new york times drugs depression